Electronic databases were searched from their inception until May 2017. Included studies reported on the immediate biomechanical effects of different degrees of lateral wedge insoles during walking in people with knee osteoarthritis. The main measures of interest relating to the biomechanics were the first and second peak of external knee adduction moment and knee adduction angular impulse. For the comparison of the biomechanical effects of different degrees of insoles, the studies were divided in three subgroups: insoles with a degree higher than 0° and equal to or lower than 5°; insoles higher than 5° and equal to or lower than 9°; and insoles higher than 9°. Eligible studies were pooled using random-effects meta-analysis. Results

Sizes: 5 to 15 (Unisex) | Arch Type: High, neutral, low | Anti-Odor: Yes | Materials: Recycled plastic, foam, synthetic | Our Overall Rating: 4.7/5 We can't sell you a pair of 2 lefts, but you could simply flip the right one upside-down and use it as a left. Sizes: One size | Arch Type: Not listed | Anti-Odor: Yes | Materials: Terrycloth, foam | Our Overall Rating: 4.2/5 Sizes: Men's 4.5 to 14.5, Women's 5.5 to 15.5 | Arch Type: High | Anti-Odor: Yes | Materials: Polyurethane foam, gel, plastic | Our Overall Rating: 4.8/5 While we love that these insoles conform to your specific foot shape, we noticed that it takes a few wears (up to 10 hours, according to the brand) before they soften and change shape.Lateral Sole Wedge Inserts can be worn in any shoe and beneath existing insoles or prescription orthotics. Lateral Sole Wedge Inserts limit supination and increase ankle stability by placing a semi-firm valgus wedge under the entire lateral aspect (outside) of the foot. The wedge has a 3-degree forefoot and rearfoot lateral (valgus) post. Designed to ease pain and reduce shoe wear. Made of a dense Poron foam and nylon top cover. Latex-free. May be trimmed to fit. By Myfootshop.com. 1 pair/pkg. Washing Instructions: Hand wash in warm water with dish soap or use a wet wipe to restore adhesive surface. Air dry completely before reapplying.

Picavet HS, Hoeymans N. Health related quality of life in multiple musculoskeletal diseases: SF-36 and EQ-5D in the DMC3 study. Ann Rheum Dis. 2004;63(6):723–9. Sizes: Men’s: 5.5 to 17, Women’s 4.5 to 14 | Arch Type: High | Anti-Odor: Yes | Materials: Polyester, foam | Our Overall Rating: 5/5 Remove the existing insole from the shoes you wish to use your new insoles with (please note that not all insoles are removable) Sasaki T, Yasuda K. Clinical evaluation of the treatment of osteoarthritic knees using a newly designed wedged insole. Clin Orthop Relat Res. 1987;221:181–7. We noticed that these insoles tend to slip when we remove our shoes. Still, they're easy to readjust as needed.The main objective of this review was to understand whether the amount of the angulation of the wedge influenced the EKAM and KAAI in patients with medial knee OA. It was our hypothesis that larger angulations would lead to a higher effect. However, the effect size of insoles with wedges ≤5° (SMD = − 0.22) and the effect size of insoles with wedges > 9° (SMD = − 0.30) are very similar for the first peak and for the second peak EKAM. For KAAI, because was retrieved only one study ( n = 18) [ 25] that studied insoles with a wedge greater than 9°, it is not possible to form any conclusion. An emerging problem that would require further analysis is related to the correct adjustment of the insoles to each patient. Apparently, there is no research investigating an optimal dose–response concerning the degree of lateral wedge insoles for each patient based on biomechanical factors. From our knowledge, only one study attempted to examine the effect of incrementally increasing lateral wedge amounts on EKAM [ 47]. However, a key limitation of that study was that the participants were healthy and young. The authors tested seven inclinations of lateral wedging (0°, 2°, 4°, 6°, 8°, 10°, 12°). Yet, it is curious that with an insole angled at 2°, the average reduction was surprisingly 6.4% in the first peak EKAM and 5.1% in the KAAI, values that are similar when compared to studies with participants with medial knee OA, where insoles with angles of 5° and 6° are typically applied [ 8, 13, 26]. Some studies have attempted to apply lateral wedge insoles in a customization way but based on other indicators such as subjective comfort, pain relief, or static pedometer evaluation [ 16, 19, 48, 49, 50]. Their conclusions seem more promising than traditional applications based only on one degree for all individuals. In the study by Barrios et al. [ 48], the authors observed an increased EKAM over time (1 year) in the control group but not in the intervention group and, within the intervention group, the mechanical effectiveness of the lateral wedging did not decrease over time. Iijima H, Fukutani N, Aoyama T, Fukumoto T, Uritani D, Kaneda E, et al. Clinical phenotype classifications based on static Varus alignment and Varus thrust in Japanese patients with medial knee osteoarthritis. Arthritis Rheumatol. 2015;67(9):2354–62.